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Successful Phase One Demonstrates Tumor Response with Increased Overall Survival for Lead VBL Therapeutics Compound in Cancer

…ehind this anti-angiogenic virotherapy is truly unique” said Pierre Triozzi, M.D., Solid Tumor Oncology Department, Cleveland Clinic, and the principal investigator in the Phase 1 trial. “We have seen antitumor activity after only one dosing, with an excellent safety profile. VB-111 has a real potential for clinical development to treat a variety of advanced metastatic cancers”. The trial has found VB-111 to be safe and well tolerated up to the ma…


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…We are a clinical-stage biopharmaceutical company focused on the discovery, development and commercialization of first-in-class treatments for areas of unmet need in cancer and immune/inflammatory indications. Our product candidates Our lead candidate is VB-111, a gene-based biologic agent for solid tumor indications which we have advanced to programs for ovarian cancer, recurrent glioblastoma, colon cancer and thyroid cancer. Ovarian cancer GBM…


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VBL Therapeutics Announces Novel Mechanistic Data for VB-201, A First in Class Orally Available Anti-Inflammatory Compound that Inhibits CD14-TLR4 and TLR2-Dependent Innate Cell Activation

…these innovative results with the immunology community, said Eyal Breitbart, PhD, VBL’s VP for R&D. “VBL’s intensive research on anti-inflammatory mechanisms has led us to the development of the Lecinoxoid pipeline of small molecules, which modulate the underlying pathway that leads to inflammation in many immune inflammatory diseases. Moreover, Due to its MOA, VB-201 may add significant value to atherosclerosis patients on top of statins.” The co…


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VBL Therapeutics to Present at Upcoming June Conferences

…EWSWIRE) — VBL Therapeutics (Nasdaq:VBLT) today announced Prof. Dror Harats, CEO, will provide a corporate overview at the 2017 BIO International Convention in San Diego and participate in a panel on novel approaches in immuno-oncology at the JMP Securities Life Sciences Conference in New York City. 2017 BIO International Convention Presentation Details Date: Tuesday, June 20, 2017 Time: 11:45 a.m. PDT Presentation Room: Company Presentation Theat…


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VBL Therapeutics Announces Positive Preclinical Data for VB-201 against Psoriasis — First in New Class of Orally Available Anti-Inflammatory Compounds

…2010 Society for Investigative Dermatology (SID) Annual Meeting, in Atlanta, Ga., by Eyal Breitbart, Ph.D., vice president of research at VBL.     VB-201 is the lead candidate of several proprietary phospholipid analogs from VBL’s proprietary Lecinoxoid platform. Recent studies have indicated that oxidized phospholipids can downregulate the production of pro-inflammatory cytokines by mature dendritic cells. VB-201 acts by inhibiting the production…


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VBL Therapeutics Receives FDA Fast Track Designation for Lead Compound VB-111

…ovel therapy to treat this serious and devastating cancer” said Dror Harats, MD, VBL’s Chief Executive Officer. “Building on the promising data from our Phase 2 trial, we plan ahead for a pivotal trial with VB-111 for rGBM under the Fast Track program which should expedite the development of VB-111.” In addition to GBM, VB-111 is also evaluated in multi-dose Phase 2 clinical trials for differentiated thyroid cancer and ovarian cancer. About VB-111…


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VBL Therapeutics Initiates Phase 2 Clinical Trial of VB-201 in Patients with Psoriasis

…important treatment advance for patients with psoriasis,” said Dror Harats, M.D., chief executive officer of VBL Therapeutics. “Building on the promising results observed preclinically and the success of our four separate Phase 1 clinical studies, we are excited to advance VB-201 into Phase 2 development for psoriasis. We look forward to launching clinical trials in additional indications in the near-term, as well as entering Phase 2 clinical dev…


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VBL Therapeutics to Report First Quarter 2015 Financial Results on May 12, 2015

TEL AVIV, Israel, May 5, 2015 (GLOBE NEWSWIRE) — VBL Therapeutics (Nasdaq:VBLT), a clinical-stage biotechnology company committed to the discovery, development and commercialization of first-in-class treatments for cancer, today announced that it will host a conference call and live audio webcast on Tuesday, May 12, 2015 at 8:30 a.m. ET to report first quarter 2015 financial results. To participate in the conference call, please dial 1-877-280-2…


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VBL Therapeutics Reports Updated Interim Results From Phase 2 Clinical Trial of VB-111 in Recurrent Glioblastoma (rGBM)

…VB-111 in combination with bevacizumab (Avastin®) upon disease progression, compared to patients treated with VB-111 followed by bevacizumab alone (p=0.05). These study results will be presented in greater detail at VBL’s Analyst and Investor Meeting today, Monday, June 1, 2015, in conjunction with the 2015 American Society for Cancer Oncology (ASCO) Annual Meeting. “We are very pleased to see a statistically significant overall survival benefit…


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VBL Therapeutics to Webcast Analyst and Investor Event at American Society of Clinical Oncology (ASCO) Annual Meeting on June 1, 2015

…under the Investor Relations section of the Company’s website at www.vblrx.com, and an archived replay of the webcast will be available for 30 days after the presentation. About VBL: Vascular Biogenics Ltd., operating as VBL Therapeutics, is a late-stage clinical biopharmaceutical company focused on the discovery, development and commercialization of first-in-class treatments for cancer. VBL has also developed a proprietary platform of small molec…